We are interested in the dynamics of syphilis transmission to better understand why rates of infection continue to rise in various cities across the globe.
So we are looking at re-infection as a way to glean information about how challenging or not it might be to achieve epidemic control:
- Feldman J, Mishra S. (2019). What can the proportion of re-infections tell us about the basic reproductive number in syphilis epidemics: a modeling study. (Trainee publication). Infect Dis Model, 4, 257-264.
And the potential impact of implementing different strategies to reduce transmission at a population-level. Here is what we learned so far re: screening strategies:
- Tuite AR, Shaw S, Ross C, Reimer J, Fisman D, Mishra S. (2018). Can enhanced screening of men with a history of prior syphilis infection stem the epidemic in men who have sex with men? A mathematical modelling study. Sex Transm Infect, 94(2), 105-110. [PDF access]
- Tuite AR, Fisman DN, Mishra S. (2013). Screen more or screen more often? Using mathematical models to inform syphilis control strategies. BMC Public Health, 13, 606.
Mishra Lab 